medicine name: Co Amoxiclav

Brand name: clamox ®

Drug category:

Class of penicillin antibiotics

Indications:

Sinusitis, tonsillitis and otitis media infections

Respiratory infections such as bronchitis and pneumonia

Genitourinary tract infections

Tooth infection

Skin and soft tissue infections

Infections of the joints and bones

Mechanism of action:

clamox® is a broad-spectrum antibiotic consisting of a penicillin (amoxicillin) and a beta-lactamase (clavulanic acid) inhibitor.

By binding to the penicillin-binding protein, amoxicillin inhibits the synthesis of bacterial cell wall peptides and glycans, thereby destroying bacteria. Clavulanic acid is a beta-lactamase inhibitor that alone does not have much antibiotic power, but in combination with penicillins it increases their potency.

Pharmacokinetics:

It is metabolized in the liver and excreted in the urine.

Administration:

The dose of each drug is determined by your doctor. However, the usual dose of the drug is as follows:

For the treatment of infections in adults and children over 12 years:

Moderate infections: one 375 mg tablet every 8 hours or one 625 mg tablet every 12 hours

Severe infections: 625 mg tablets every 8 hours

To minimize gastrointestinal side effects and maximize the absorption of clamox®, it is recommended that the drug be taken at the beginning of a meal.

No dose adjustment is required in patients with renal insufficiency who require creatinine clearance greater than 30 ml / min.

In children, it is recommended to use the suspension of this drug.

Contraindication:

It is contraindicated in patients with penicillin allergy and a history of clamox® allergy.

Dose adjustment should be made in patients with renal insufficiency with creatinine clearance less than 30 ml / min.

Warning:

Consult your doctor or pharmacist if you have any conditions such as liver failure, kidney failure, allergies, gastrointestinal diseases and a history of gastrointestinal bleeding.

Consult your doctor or pharmacist before testing your blood sugar.

If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, take the prescribed dose and avoid doubling the dose.

For complete recovery from purulent sore throat infections, treatment should be continued for at least 10 days to prevent acute rheumatic fever.

Drug interactions:

If taking this medicine with tetracyclines at the same time, consult your doctor or pharmacist.

side effects:

Each drug may cause some side effects in addition to the therapeutic effects. Although not all side effects are seen in one person, consult your doctor or pharmacist if you experience any of the following:

Nausea, diarrhea and headache

Pregnancy and lactation:

This drug is in the B category of pregnancy and the use of this drug in pregnancy and lactation is allowed by observing safety tips for mother and fetus and under the supervision of the treating physician.

Dosage form:

clamox ® 375 mg coated tablets are available in packs of 20.

clamox ® 625 mg film-coated tablets are available in packs of 20.

Storage:

Keep the tablets away from light, moisture and at a temperature below 30 ° C.

Keep the tablets in the box until used.

Keep out of the reach of children.

Manufacturer:

Daana Pharma Co.