Raw Materials Research Director and Technical Officer

Name: siamak

Family Name: Jasouri

Gender: Male

Marital Status: Married

Date of birth: 14 may 1972

Place of birth: Tabriz - Iran

Nationality: Iranian

Native language: Persian & Turkish (Azari)

CURRENT POSITION: R & D Manager and head of GMP Department

Candidate for responsible pharmacist

Office Add. : DAANA PHARMACEUTICAL Co., 15th Km of Tabriz – Tehran Road Tabriz- Iran

Phone: 0098-411-6300586-9

Mobile Phone: 0098-9143143038

Fax: 0098-411-6300591

Email Add.1: jassouri@yahoo.com

Email Add.2: jasouri@daanapharma.com
Homepage: www.daanapharma.com
Education

2004-2010

Ph.D. degree in Organic Chemistry (drug synthesis) from Urmia University in Iran under Prof. Khalafi's supervision with grade of 18.17/20. The title of thesis is "The novel synthesis and characterization of Chloro- Indanone derivatives as GABAb receptor"

1995 – 1997

M.Sc. degree in Organic Chemistry from Urmia University in Iran under Prof. Khalafi's supervision with grade of 18.22/20 as top student, "Synthesis and caracterization of 2-Acyl-1,4- naphtalenediones and their reactions with alcohols" (as precursors for psoriasis disease)

1991 – 1995

B.Sc. degree in Pure Chemistry from Tabriz University, Tabriz-Iran, with grade of 14.90/20.

1979 – 1990

High School Diploma in natural science from valfajr (safa) highscool, Tabriz, Iran with grade of 17.48/20.

Training courses

1) Production, Operation, GMP for clean rooms in JE ILL JEDONG CO., S.KOREA.

2) Production Management in Industrial Mangement Organization, Tabriz, Iran.

3) Validation in Pharmaceutical Co. RAHAVARAN AFAG Institute.

4) New Systems in Production management in NOOR Research and education Institute.

5) Scale up in Chemical Process educated by Dr. Zahid Abdolmanaf Sheikh from India

6) Process Management by TUV NORD Academy

7) Inspection and Audit according to IMS by KEIFIAT SAZ Cosultant Co.

8) Self Inspection for OHSAS 18001:2007 by Pooyan Training Institute.

9) variouse courses for Clean room, Cleaning Validation, Process Validation, GMP presented by Dr. A. Mehdizadeh

10) Self Inspection for ISO9001-2000

11) EFQM

12) Product Quality Review

13) Quality Risk Management

14) Quality Mnagement System

Honors and awards:

I've got letters of commendation for successful effort in carrying out the research on projects from Identification Office (NAJA), Inspection and Discovery of crimes of Iranian Police Force.

I've got scholarship from DAANA Pharmaceutical Co. for Ph.D.

Projects:

It was explaned in experience section.

Books:----

Articles:

1) S.Jasouri, “ Restoration of obliterated serial numbers by catalized acid etching”, presented in congress of Inspection and Discovery of crimes of Iranian Police Force(NAJA).1999.

Published in Iranian journal,Karagah, 1381(1).

2) M. Moogooee, H. Ramezanzadeh, S. Jasouri, Y. Omidi, S. Davaran, “ Synthesis and In Vitro Studies of Cross-Linked Hydrogel Nanoparticles Containing Amoxicillin”, JOURNAL OF PHARMACEUTICAL SCIENCES, 2010, DOI 10.1002/jps.22351, Wiley-Liss, Inc. and the American Pharmacists Association.

3) S. Jasouri, J. Khalafy, M. Badali and M. Piltan, “ Selective Bromination of 4- Chloro-1- indanone and synthesis of (4- Chloro- 2, 3- Dihydro-1H- indene-2- yl) methanamine”, S. Afr. J. Chem., 2010, 63, 83-87.

4) S. Jasouri, J. Khalafy, M. Badali and R.H. Prager, “Synthesis of 9H- indeno [1,2-b] pyrazine and 11H- indeno [1,2-b] quinoxaline derivatives in one step reaction from 2- bromo- 4- chloro -1- indanone” , (S. Afr. J. Chem., 2011, 64,105-107)

5) S. Jasouri, J. Khalafy, M. Badali and S. Davaran, “ UV spectroscopic studies on anthralins stabilities, Turkish Journal of Chemistry”, (in press)

Congress:

1) S. Jassouri and J. Khalafy, “ Synthesis and caracterization of 2- Acyl 1,4- Naphtalendiones”, presnted in 6th. Iranian seminar of Organic chemistry, 19- 21 Aug. 1997.

2) S. Jassouri and J. Khalafy, “ Reaction of alcohols with Formyl and Acetyl 1,4- Benzoquinone and 2- Acyl-1,4-Naphtalendiones” , presented in 6th. Iranian seminar of Organic chemistry, 19- 21 Aug. 1997.

3) S. Jassouri, “ Desighn and modification of mobile forensic laboratory. presented in congress of Inspection and Discovery of crimes of Iranian Police Force (NAJA) 1999.

4) S. Jassouri and J. Khalafy, "Synthesis of 2-(2-aminoalkyl)-4-chloro-2,3-dihydro -1H-inden-1-one", 16th Iranian seminar of Organic chemistry

5) S. Jassouri, M. Badali and J. Khalafy, "Simple and Regioselective Bromination of 4-chloro indan-1-one ", 17th Iranian seminar of Organic chemistry

6) S. Jassouri, M. Badali and J. Khalafy, " Synthesis of 9H-indeno[1, 2-b]pyrazine and 11H-indeno[1, 2-b]quinoxaline derivatives in one step reaction from 2-bromo-4-chloro-1-indanone" 17th Iranian seminar of Organic chemistry

7) M. Badali, M. Aghazadeh, S. Jasouri, P. Salehpour, "Synthesis of C-3 substituted 7-(2-(1H-indol-3-yl) acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxilic acid as e new β-Lactam antibiotics" 17th Iranian seminar of Organic chemistry

Tests and Techniques:

Set up of Injectional Sterile plant as clean room industrial production plant in Daana pharmaceutical Co. (Zakaria- Tabriz Pharmaceutical Co.)

Professional Membership:

I am member of Iranian chemistry and chemical engineering society.

Position Held:

1) Production Expert(1378-1379)

2) Head of Sterile Production Plant(1379-1384)

3) API R&D Manager(1384-…)

4) Head of GMP ( 1390- …)

5) F.D R&D Manager(1391-…)

6) Responsible pharmacist (1391- …)

Professional Interest:

Organic synthesis, Pharmaceutical Chemistry, synthesis of drug, Scale up of Reactions (bench and pilot scale), Quality Assurance, Quality Management System.

Professional Experiences:

2012 till now

I have managed as F.D R&D manager some projects in my Co. and I'v been as API Responsible Pharmacist/Qualified Person in QA.

2005 to 2012

I have managed as API R&D manager some projects in my Co. and research on GABA receptors and synthesis of some injectible cephalosporins such as cefepime, HCl- cefuroxime, Na – ceftizoxime, Na, and clavlanate potasium.

2001 to 2005

I was as a Sterile and injectional plant manager and produced the numbers of β-Lactam antibiotics in industrial scale. I passed educational course in South Korea for clean room treatment in Je Il Jedong Co. . Also, I have researched about some intermediates used for synthesising of antibiotics.(e.g. 7-ACT for ceftriaxone-Na , 7-TDA for Cefazoline-Na, 7-AVCA for Cefixime)

1999 to 2001

I was doing research as production expert in production part and R&D laboratory in Zakaria Pharm. and Chemical Co., Tabriz, Iran.The research involved the synthesis and modification of the numbers of β-Lactam antibiotics from penicillin and cephalosporin groups such as: Cephalexin,H2O - Ampicillin,3H2O – Amoxicillin,3H2O – Cloxacillin,Na- Cefradine – Cefixime,H2O as a Oral Drug and Ampicillin,Na - Amoxicillin,Na – Cefazoline,Na – Ceftazidim,5H2O - ceftriaxone,Na – Cefotaxime,Na – Ceftizoxim,Na – as a Sterile and Injectional Drug.

1997 – 1999

I was in military service in forensic laboratory of Police Force, In Tehran, Iran.I studied and researched about characterization of narcotic compound such as Cannabis, Morphine codeine,..

I designed and assembled mobile forensic laboratory for sampling and testing of doccument, and other useful material for proving.

I presented the new method about restoration of oblitrated serial numbers by catalized acid etching.

1995 – 1997

I studied on the synthesis and caracterization of quinone compound such as: Benzoquinones, Naphtaqunones, Antraquinones, Tetracyclic compound and their Acyl derivatives and their reactions with alcoholes, also I investigate about mercapto derivatives of Antralins as a drugs for Psoriasis, during M.Sc. course.

I also demonstrated as teaching assistant for B.Sc students in Chemistry Dept. of Urmia University.

Inventions and Patent:

Novel synthesis of cefazolin sodium via crystalization method, European Patent, (under submission)

Skill

1) Production management
2) Process management

3) ISO, OHSAS, 5S, KAIZEN

4) Pharmaceutical Inspection

5) Quality Assurance